Of course! Buying safely is all about how you pay. The vast majority of sellers on eBay accept PayPal or credit cards. If you pay with your credit card, you're completely protected against fraud (no item, or item substantially different than described). Finally, on payments, never ever pay with cash!
eBay offers a 100% satisfaction guarantee on all purchases, regardless of what individual sellers set up as their return policy. eBay's goal is for customers to be completely satisfied with their purchases and return to the site to purchase more items in the future. Sellers are able to set up certain policies and procedures so make sure you read the seller's policies before purchasing, and again before initiating a return.
Most times you will have nothing to go on and you will have to place your trust in the eBay Seller. This is especially true of new Sellers and Sellers who only sell a few items and never build up a track record. EBay calls these Feedbacks. The feedback can be labeled as Positive, Neutral, or Negative. Make sure your seller has a positive feedback score.
ebay encourages sellers to ship an item as soon as they receive a payment. Most sellers ship within 7 days. (Allow extra time for international shipments.) Depending on the shipping service the seller uses, you may be able to track your item online.